Ibutamoren (MK 677)
Ibutamoren, better known as “MK-677”, is the strongest and most potent orally administered growth hormone secretagogue when it comes to selective androgen receptor modulators, also known as “SARMs”. Put simply, a secretagogue is a substance that chemically signals the pituitary gland to increase secretion of the growth hormone MK-677. This could be compared to peptides like GHRP-6 or ipamorelin, only that it doesn’t require injections and doesn’t have any side effects. MK-677 was originally developed by Reverse Pharmacology and was aimed at combating conditions such as muscle wasting, obesity, osteoporosis and, oddly enough, treating elderly patients with hip fractures.
In the bodybuilding and sports world, Ibatamoren is used as a side effect-free alternative to steroids.
The most common doses of MK-677 are between 5 and 30 mg per day. In a few instances we’ve seen doses greater than 50 mg per day, but these are rare and have not resulted in exponential benefits over the recommended top-end dosage of 20-30 mg per day.